Description

[4As,8Ar,(+)]-Decahydroquinazoline is a high-purity, stereochemically defined heterocyclic compound belonging to the quinazoline class. This specific enantiomer is a valuable chiral building block and intermediate in advanced organic synthesis, prized for its rigid, fused bicyclic structure. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for research and development, particularly in the synthesis of complex molecules requiring precise stereochemical control.

Application

• Pharmaceutical Intermediate: Serves as a key chiral scaffold in the research and synthesis of novel active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and antiviral targets.
• Agrochemical Synthesis: Used as a sophisticated building block in the development of advanced pesticides and herbicides with enhanced stereospecific activity.
• Catalyst & Ligand Development: Employed in the design and preparation of novel chiral catalysts and ligands for asymmetric synthesis applications.
• Fine Chemical Production: Acts as a critical intermediate in the multi-step synthesis of complex specialty chemicals and flavors & fragrances.
• Academic & Industrial R&D: A valuable compound for methodological studies in organic chemistry, including novel cyclization and functionalization reactions.
• Material Science Precursor: Investigated for use in the synthesis of advanced organic materials and molecular devices due to its stable, nitrogen-containing heterocyclic core.

Basic Information

Product Name	[4As,8Ar,(+)]-Decahydroquinazoline
CAS No.	26685-89-2
Molecular Formula	C8H14N2
Molecular Weight	138.21 g/mol
Synonyms	(+)-cis-Decahydroquinazoline; (4aS,8aR)-Decahydroquinazoline; (S,R)-Decahydroquinazoline; 1,2,3,4,4a,5,6,7,8,8a-Decahydroquinazoline; Perhydroquinazoline; Tetrahydroimidazo[1,2-a]pyrimidine (fully saturated); Quinazolidine; Bicyclic diamine
EINECS	Contact for details

Quality Control

Our [4As,8Ar,(+)]-Decahydroquinazoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), enantiomeric excess, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.