Description

Methyl L-Lysinate Dihydrochloride is a protected derivative of the essential amino acid L-lysine, widely utilized as a key chiral building block in organic synthesis. Its primary value lies in providing a reactive ester group while protecting the amine functionalities, enabling controlled peptide coupling and the synthesis of complex bioactive molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical industries developing novel peptides, drug candidates, and biochemical tools.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of peptide-based active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used in proteomics and peptide chemistry research for constructing specific peptide sequences and studying enzyme-substrate interactions.
• Fine Chemical Synthesis: Serves as a chiral synthon in the asymmetric synthesis of complex organic molecules and natural product analogs.
• Protecting Group Strategy: The methyl ester and dihydrochloride salt forms provide orthogonal protection for lysine side chains in multi-step synthetic routes.
• Reference Standard: Can be employed as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.

Basic Information

Product Name	Methyl L-Lysinate Dihydrochloride
CAS No.	26348-70-9
Molecular Formula	C7H18Cl2N2O2
Molecular Weight	233.14 g/mol
Synonyms	L-Lysine methyl ester dihydrochloride; Methyl (2S)-2,6-diaminohexanoate dihydrochloride; H-Lys-OMe·2HCl; Methyl L-lysine dihydrochloride; (S)-Methyl 2,6-diaminohexanoate dihydrochloride; Lys-OMe·HCl; Methyl ester of L-lysine hydrochloride; 2,6-Diaminohexanoic acid methyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Methyl L-Lysinate Dihydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity. We provide comprehensive quality documentation, including Certificates of Analysis (COA) with detailed results from HPLC, chiral analysis, and other relevant tests. The product is suitable for use under cGMP conditions for pharmaceutical development, and we can support custom purity requirements to meet specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed immediately after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+15.0° to +20.0° (c=1 in H2O)
Chiral Purity (HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.