Description

Z-Lys-Ome Hcl is a protected derivative of the essential amino acid L-lysine, specifically the Z-protected methyl ester hydrochloride salt. This compound is a crucial building block (amino acid derivative) in peptide synthesis, offering controlled reactivity for the sequential assembly of complex peptide chains. It is primarily utilized by pharmaceutical researchers, peptide chemists, and fine chemical manufacturers engaged in the development of therapeutic peptides, biochemical probes, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A fundamental reagent for the controlled incorporation of lysine residues into peptide sequences.
• Solution-Phase Peptide Synthesis: Used in traditional coupling methodologies for constructing specific peptide fragments.
• Pharmaceutical Intermediate: Serves as a key raw material in the research and production of peptide-based active pharmaceutical ingredients (APIs).
• Bioconjugation & Labeling: The reactive amine (after deprotection) can be used to attach labels, tags, or other molecules to peptides or proteins.
• Biochemical Research: Employed in academic and industrial labs for studying protein structure-function relationships and enzyme-substrate interactions.
• Production of Custom Peptides: Essential for contract research and manufacturing organizations (CROs/CMOs) offering bespoke peptide services.

Basic Information

Product Name	Z-Lys-Ome Hcl
CAS No.	26348-68-5
Molecular Formula	C15H22N2O4 • HCl
Molecular Weight	330.81 g/mol
Synonyms	Nα-Carbobenzyloxy-L-lysine Methyl Ester Hydrochloride; Z-L-Lys-OMe • HCl; Cbz-L-Lysine Methyl Ester Hydrochloride; Nα-Cbz-L-lysine Methyl Ester Hydrochloride; (2S)-6-Amino-2-[[(benzyloxy)carbonyl]amino]hexanoic acid methyl ester hydrochloride; Methyl N2-[(benzyloxy)carbonyl]-L-lysinate hydrochloride; Z-Lys-OMe•HCl
EINECS	Contact for details

Quality Control

Our Z-Lys-Ome Hcl is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive applications like peptide synthesis. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation [α]D20	+10.0° to +12.0° (c=1 in AcOH)
Melting Point	~105-110°C
Heavy Metals (as Pb)	≤20 ppm
Residue on Ignition	≤0.1%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.