Description

Ethyl L-Serinate Hydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of L-serine. This compound is a crucial chiral building block in organic synthesis, valued for its role in introducing the serine moiety while protecting the carboxylic acid and amino functionalities. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of peptides, peptidomimetics, and other bioactive molecules.

Application

• Pharmaceutical Intermediates: A key chiral synthon in the research and development of active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease therapeutics.
• Peptide Synthesis: Serves as a protected serine residue in solid-phase and solution-phase peptide synthesis (SPPS) for constructing complex peptide sequences.
• Bioconjugation & Linker Chemistry: Used in the preparation of antibody-drug conjugates (ADCs) and other bioconjugates where a serine-based linker is required.
• Proteomics Research: Employed as a standard or reagent in mass spectrometry and other analytical techniques for studying protein structure and function.
• Fine Chemical Synthesis: Acts as a starting material or intermediate in the synthesis of specialty chemicals, catalysts, and ligands for asymmetric synthesis.
• Cosmetic Peptides: A potential raw material in the synthesis of bioactive peptides for advanced skincare and cosmetic formulations.

Basic Information

Product Name	Ethyl L-Serinate Hydrochloride
CAS No.	26348-61-8
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	L-Serine ethyl ester hydrochloride; (S)-2-Amino-3-hydroxypropanoic acid ethyl ester hydrochloride; Ethyl (S)-2-amino-3-hydroxypropanoate hydrochloride; Serine ethyl ester HCl; H-Ser-OEt·HCl; Ethyl ester of L-serine hydrochloride; 2-Amino-3-hydroxypropionic acid ethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our Ethyl L-Serinate Hydrochloride is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Solubility	Freely soluble in water, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.