Description

n-Acetyl-D-Cysteine is the D-enantiomer of the common mucolytic agent N-acetylcysteine, distinguished by its specific stereochemistry. This compound is a valuable chiral building block and a critical reference standard for analytical and research purposes, where the differentiation between enantiomers is essential. It serves the needs of pharmaceutical R&D laboratories, analytical chemists, and manufacturers of fine chemicals and diagnostic reagents who require high-purity, stereochemically defined materials.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and enantiomeric purity testing of N-acetylcysteine in pharmacopeial methods (USP, EP).
• Chiral Synthesis: Acts as a key chiral intermediate or precursor in the asymmetric synthesis of more complex pharmaceutical compounds and bioactive molecules.
• Biochemical Research: Employed in enzymatic and metabolic studies to investigate the stereospecificity of biological pathways involving cysteine derivatives.
• Analytical Method Development: Serves as a critical standard for developing and validating chiral separation methods, such as HPLC or CE, to distinguish between D- and L- enantiomers.
• Diagnostic Reagent Manufacturing: Utilized in the production of specific diagnostic kits and reagents where the D-enantiomer is required as a control or component.

Basic Information

Product Name	n-Acetyl-D-Cysteine
CAS No.	26117-28-2
Molecular Formula	C5H9NO3S
Molecular Weight	163.19 g/mol
Synonyms	(R)-2-Acetamido-3-mercaptopropanoic Acid; D-NAC; N-Acetyl-D-cysteine; N-Acetyl-D-3-mercaptoalanine; (R)-N-Acetylcysteine; Acetylcysteine D-form; (2R)-2-Acetamido-3-sulfanylpropanoic Acid; ADC
EINECS	Contact for details

Quality Control

Our n-Acetyl-D-Cysteine is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity assay, identity confirmation, and impurity profiling to ensure it meets stringent specifications for research and analytical use. Certificates of Analysis (COA) with detailed chromatographic data (e.g., HPLC for enantiomeric excess) are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent absorption of atmospheric moisture, which may affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Purity (Chiral HPLC)	≥99.0% (D-isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.