Description

Gentamicin C1A is a primary active component of the broad-spectrum aminoglycoside antibiotic complex, gentamicin. This compound is critical for its potent bactericidal activity against a wide range of Gram-negative and some Gram-positive bacteria. It is an essential raw material for pharmaceutical manufacturers in the production of injectable antibiotics, ophthalmic solutions, and topical formulations. Consistent quality and reliable supply are paramount for ensuring the efficacy and safety of the final medicinal products.

Application

• Active Pharmaceutical Ingredient (API): Core component in the synthesis of gentamicin sulfate and other gentamicin-based antibiotic formulations.
• Pharmaceutical Intermediates: Used in the research, development, and commercial manufacturing of injectable antibiotics for systemic infections.
• Veterinary Medicine: Employed in the production of antimicrobial treatments for livestock and companion animals.
• Ophthalmic Preparations: Key ingredient in eye drops and ointments for treating bacterial conjunctivitis and other ocular infections.
• Topical Antimicrobials: Formulated into creams, ointments, and sprays for skin and wound infections.
• Reference Standard: Serves as a high-purity chemical standard for quality control and analytical testing in laboratories.
• Biochemical Research: Utilized in microbiological studies to investigate bacterial protein synthesis and mechanisms of antibiotic action.

Basic Information

Product Name	Gentamicin C1A
CAS No.	26098-04-4
Molecular Formula	C21H43N5O7
Molecular Weight	477.60 g/mol
Synonyms	Gentamicin C1; Gentamycin C1a; O-2-Amino-2-deoxy-α-D-glucopyranosyl-(1→4)-O-[3-deoxy-3-(methylamino)-α-D-xylopyranosyl-(1→6)]-2-deoxy-D-streptamine; Antibiotic G 418 Component C1a; Sch 9724 Component C1a; Garamycin Component C1a; Gentamicin C1a Sulfate (salt form)
EINECS	Contact for details

Quality Control

Our Gentamicin C1A is manufactured and tested under strict quality management systems. We offer material suitable for pharmaceutical applications, with specifications that can meet relevant pharmacopoeial standards (e.g., USP, EP, BP) upon request. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing purity, potency, and impurity profiles to ensure compliance with your specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Specific Rotation	+120° to +135°
Related Substances (HPLC)	Individual impurity ≤ 2.0% Total impurities ≤ 5.0%
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.