Description

2,4-Dihydroxy-L-Phenylalanine is a specialized, non-proteinogenic amino acid derivative of L-DOPA, featuring additional hydroxylation at the 4-position of the aromatic ring. This structural modification makes it a valuable chiral building block and intermediate for advanced pharmaceutical synthesis and biochemical research. It is primarily sought by research institutions and manufacturers in the life sciences sector for developing novel therapeutic agents and conducting metabolic studies.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of potential drug candidates targeting neurological and metabolic disorders.
• Biochemical Research: Used as a substrate or standard in enzymatic studies related to tyrosine and dopamine metabolism pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical laboratories.
• Organic Synthesis: A versatile building block for constructing complex molecules in medicinal chemistry and asymmetric synthesis.

Basic Information

Product Name	2,4-Dihydroxy-L-Phenylalanine
CAS No.	26049-87-6
Molecular Formula	C9H11NO5
Molecular Weight	213.19 g/mol
Synonyms	L-2,4-Dihydroxyphenylalanine; 2,4-Dihydroxy-L-DOPA; (2S)-2-Amino-3-(2,4-dihydroxyphenyl)propanoic acid; 2,4-DiOH-L-Phe; 3-(2,4-Dihydroxyphenyl)-L-alanine
EINECS	Contact for details

Quality Control

Our 2,4-Dihydroxy-L-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store the product under an inert atmosphere for long-term preservation. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.