Description

4-Amino-2,5,6-trifluoropyrimidine is a high-value fluorinated pyrimidine building block essential for advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical sectors where the introduction of fluorine atoms is critical for modulating biological activity and stability. It is primarily needed by R&D chemists and process development scientists working on novel heterocyclic compounds, fluorinated drugs, and specialty agrochemicals.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of fluorinated nucleoside analogs and other bioactive molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for developing novel fluorinated polymers and liquid crystals with unique properties.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects requiring specific fluorinated pyrimidine scaffolds.

Basic Information

Product Name	4-Amino-2,5,6-trifluoropyrimidine
CAS No.	25935-33-5
Molecular Formula	C4H2F3N3
Molecular Weight	149.08 g/mol
Synonyms	2,5,6-Trifluoro-4-pyrimidinamine; 2,5,6-Trifluoropyrimidin-4-amine; 4-Pyrimidinamine, 2,5,6-trifluoro-; 4-Amino-2,5,6-trifluoropyrimidine; 2,4,5-Trifluoropyrimidin-6-amine (tautomer); TFAP; Amino-trifluoropyrimidine
EINECS	Contact for details

Quality Control

Our 4-Amino-2,5,6-trifluoropyrimidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and stored away from direct light to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.