Description

Poly-ε-Cbz-L-Lysine is a protected derivative of the essential amino acid L-lysine, where the ε-amino group is shielded by a carboxybenzyl (Cbz) protecting group. This modification is critical for enabling controlled, stepwise synthesis in complex peptide and polymer chemistry, preventing unwanted side reactions. It serves as a key building block for researchers and manufacturers in pharmaceutical development, advanced material science, and biochemical research who require precise molecular architecture.

Application

• Peptide Synthesis: As a protected amino acid monomer for the solid-phase or solution-phase synthesis of lysine-containing peptides and proteins.
• Bioconjugation & Linker Chemistry: Utilized to create functionalized polymers or surfaces with reactive amine groups after deprotection, for attaching drugs, probes, or other biomolecules.
• Polymer & Biomaterial Research: A fundamental monomer for synthesizing specialized poly(amino acid)s and biodegradable polymers with tailored properties for drug delivery systems or tissue engineering scaffolds.
• Pharmaceutical Intermediates: Serves as a crucial intermediate in the multistep synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Biochemical Tool Development: Used to prepare enzyme substrates, inhibitors, or affinity ligands where a specific, protected lysine residue is required.
• Cross-linking Agent Precursor: After removal of the Cbz group, the free ε-amine can be used to introduce cross-links into polymers or hydrogels.

Basic Information

Product Name	Poly-ε-Cbz-L-Lysine
CAS No.	25931-47-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(Nε-Cbz-L-lysine); Poly(Nε-Carbobenzoxy-L-lysine); Poly(Nε-Z-L-lysine); PZLL; Poly(Cbz-L-lysine); Poly(ε-Cbz-L-lysine); Poly(ε-carbobenzyloxy-L-lysine); Poly(Nε-benzyloxycarbonyl-L-lysine)
EINECS	Contact for details

Quality Control

Our Poly-ε-Cbz-L-Lysine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and support our products with a detailed Certificate of Analysis (COA) upon request, confirming compliance with relevant specifications for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.