Description

2,4,4-Trifluoro-2-Trifluoromethyl-4H-Benzo[1,3]Dioxine is a specialized fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring a benzo[1,3]dioxine core with multiple fluorine substituents, makes it a valuable precursor for introducing trifluoromethyl and fluoroalkyl groups into target molecules. This high-value intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors who require precise fluorination to modulate the biological activity, metabolic stability, and lipophilicity of their compounds.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology, CNS, and antiviral drug discovery programs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides where fluorination enhances efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers, coatings, and liquid crystals with tailored properties.
• Organic Electronics: Employed in the research and development of organic light-emitting diodes (OLEDs) and semiconductor materials due to its electron-withdrawing characteristics.
• Fluorinated Liquid Crystal Development: A crucial component for creating high-performance fluorinated mesogens used in display technologies.
• Catalyst Ligand Synthesis: Used to construct sophisticated, fluorinated ligand systems for asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2,4,4-Trifluoro-2-Trifluoromethyl-4H-Benzo[1,3]Dioxine
CAS No.	25857-80-1
Molecular Formula	C9H3F6O2
Molecular Weight	266.11 g/mol
Synonyms	2,4,4-Trifluoro-2-(trifluoromethyl)-4H-1,3-benzodioxine; 4H-1,3-Benzodioxine, 2,4,4-trifluoro-2-(trifluoromethyl)-; 2-(Trifluoromethyl)-2,4,4-trifluoro-4H-1,3-benzodioxine; Benzo[1,3]dioxine, 2,4,4-trifluoro-2-trifluoromethyl-; 25857-80-1; FC-75 related intermediate; Perfluorinated benzodioxine derivative
EINECS	Contact for details

Quality Control

Every batch of 2,4,4-Trifluoro-2-Trifluoromethyl-4H-Benzo[1,3]Dioxine is manufactured and tested under a strict quality management system. We employ advanced analytical techniques including GC, HPLC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specification parameters is provided with each shipment to guarantee traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.