Description

Cholecystokinin 10 C-Terminal Fragment CAS NO 25842-57-3 is a synthetic peptide fragment corresponding to the C-terminal decapeptide of the gastrointestinal hormone cholecystokinin (CCK). This compound is a critical research tool for studying the physiological roles of CCK, including its functions in digestion, satiety signaling, and central nervous system activity. It is essential for pharmaceutical R&D, academic research, and diagnostic development in the fields of gastroenterology, neuroscience, and metabolic disorders.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the mechanisms of pancreatic secretion, gallbladder contraction, and gut motility.
• Neuroscience Studies: Applied in receptor binding assays and functional studies to explore CCK's role as a neurotransmitter or neuromodulator in the brain, related to anxiety, pain perception, and memory.
• Drug Discovery & Development: Serves as a key pharmacophore and starting material for the design and synthesis of novel CCK receptor agonists or antagonists for therapeutic applications.
• Diagnostic Kit Development: Utilized in the production of calibration standards and controls for immunoassays measuring CCK levels in biological samples.
• Biochemical Assays: Functions as a substrate or inhibitor in enzymatic studies and signal transduction pathway analysis.
• Academic & Pharmaceutical R&D: A fundamental reagent for basic science investigating gastrointestinal physiology, appetite regulation, and peptide hormone action.

Basic Information

Product Name	Cholecystokinin 10 C-Terminal Fragment
CAS No.	25842-57-3
Molecular Formula	C₅₆H₇₃N₁₁O₁₃S
Molecular Weight	1140.3 g/mol
Synonyms	CCK-10; Cholecystokinin Fragment 26-33 Amide; Sincalide; CCK Octapeptide; SQ-19,844; CCK-8 (common misnomer for the sulfated form); Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2; Cholecystokinin C-terminal decapeptide.
EINECS	Contact for details

Quality Control

Our Cholecystokinin 10 C-Terminal Fragment is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ± 10% of theoretical
Water Content (KF)	≤ 8.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.