Description

4-(4-Oxoquinazolin-3(4H)-yl)butanoic acid is a high-purity, functionalized quinazolinone derivative used as a critical building block in advanced organic synthesis. This compound is valued for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinazoline-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the quinazolinone scaffold.
• Chemical Biology & Proteomics: Serves as a valuable scaffold or linker in the design of chemical probes and molecular tools for studying biological pathways.
• Material Science: Potential monomer or additive for creating specialty polymers with unique thermal or optical properties.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for route scouting and optimization.

Basic Information

Product Name	4-(4-Oxoquinazolin-3(4H)-yl)butanoic Acid
CAS No.	25818-89-7
Molecular Formula	C₁₂H₁₂N₂O₃
Molecular Weight	232.24 g/mol
Synonyms	3-(3-Carboxypropyl)-4(3H)-quinazolinone; 4-(3H-Quinazolin-4-on-3-yl)butanoic acid; 4-(4-Oxo-3,4-dihydroquinazolin-3-yl)butanoic acid; 3-(3-Carboxypropyl)quinazolin-4(3H)-one; 4-(4-Oxo-3,4-dihydroquinazolin-3-yl)butyric acid; Quinazolinone butanoic acid derivative; 25818-89-7 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our 4-(4-Oxoquinazolin-3(4H)-yl)butanoic acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high standards, including pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.