Description

2,4,6-Tris(Trifluoromethyl)Aniline is a high-value, multi-fluorinated aromatic amine building block. This compound is prized for its unique electronic and steric properties, making it a critical intermediate in advanced material science and pharmaceutical research. It is essential for R&D and production chemists in the agrochemical, pharmaceutical, and specialty polymer industries seeking to incorporate highly fluorinated motifs for enhanced stability, lipophilicity, and bioactivity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor for synthesizing novel active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl groups to modulate metabolic stability and membrane permeability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl groups contribute to improved efficacy and environmental profile.
• Ligand & Catalyst Development: Acts as a starting material for creating sophisticated ligands in transition metal catalysis and organocatalysis, enabling challenging chemical transformations.
• Advanced Material Precursor: Employed in the synthesis of fluorinated polymers, liquid crystals, and electronic materials that demand high thermal stability, chemical resistance, and specific dielectric properties.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex, fluorinated organic molecules for various high-value applications.

Basic Information

Product Name	2,4,6-Tris(Trifluoromethyl)Aniline
CAS No.	25753-22-4
Molecular Formula	C9H4F9N
Molecular Weight	285.12 g/mol
Synonyms	2,4,6-Tris(trifluoromethyl)benzenamine; 2,4,6-Tris(trifluoromethyl)phenylamine; Aniline, 2,4,6-tris(trifluoromethyl)-; Benzenamine, 2,4,6-tris(trifluoromethyl)-; α,α,α,α',α',α'-Hexafluoro-2,4,6-trimethylaniline; 2,4,6-(CF3)3C6H2NH2; Perfluorinated aniline derivative
EINECS	Contact for details

Quality Control

Our 2,4,6-Tris(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in the original packaging or an opaque secondary container until use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.