Description

Methyl 6-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate is a high-purity, functionalized pyrimidine derivative serving as a critical building block in advanced organic synthesis. Its value lies in its dual reactive sites—the chloro and methylsulfonyl groups—which enable precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients and fine-tuning molecular properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for antiviral, anticancer, and kinase inhibitor drug candidates.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging its pyrimidine core for biological activity.
• Chemical Research & Development: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial applications.
• Material Science: Potential monomer or precursor for creating functional polymers and advanced organic materials with specific electronic properties.

Basic Information

Product Name	Methyl 6-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate
CAS No.	25742-28-3
Molecular Formula	C8H9ClN2O4S
Molecular Weight	264.68 g/mol
Synonyms	Methyl 6-chloro-2-(methylsulfonyl)pyrimidine-4-carboxylate; 6-Chloro-2-(methylsulfonyl)pyrimidine-4-carboxylic acid methyl ester; Methyl 6-chloro-2-methylsulfonylpyrimidine-4-carboxylate; 2-Methylsulfonyl-6-chloropyrimidine-4-carboxylic acid methyl ester; 4-Pyrimidinecarboxylic acid, 6-chloro-2-(methylsulfonyl)-, methyl ester; 25742-28-3; Methyl 6-chloro-2-methanesulfonylpyrimidine-4-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Chloro-2-(Methylsulfonyl)Pyrimidine-4-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We operate under a cGMP-compliant quality system to meet the rigorous demands of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.