Description

Acth (1-14) is a synthetic peptide fragment corresponding to the first fourteen amino acids of the adrenocorticotropic hormone (ACTH). This compound is a critical research tool for studying the structure-activity relationships of ACTH and its role in stimulating cortisol production from the adrenal cortex. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on endocrinology, peptide chemistry, and therapeutic development.

Application

• Biomedical Research: Used as a reference standard and active agent in studies investigating the physiological functions and signaling pathways of ACTH.
• Pharmaceutical Development: Serves as a key intermediate or starting material in the synthesis of longer ACTH analogs and potential peptide-based therapeutics.
• Endocrinology Studies: Essential for in vitro and in vivo assays to evaluate adrenal gland function and corticosteroid synthesis.
• Biochemical Reagent: Employed in enzyme kinetics studies and receptor binding assays to understand ACTH interaction with melanocortin receptors.
• Quality Control: Acts as a high-purity standard for the analysis and validation of ACTH-related products in quality control laboratories.

Basic Information

Product Name	Acth (1-14)
CAS No.	25696-21-3
Molecular Formula	C78H111N21O19S
Molecular Weight	1690.9 g/mol
Synonyms	ACTH (1-14); Adrenocorticotropic Hormone (1-14); Corticotropin (1-14); Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val; H-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-OH; Tetradecapeptide ACTH; ACTH Fragment 1-14
EINECS	Contact for details

Quality Control

Our Acth (1-14) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) documenting all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be kept in a dry environment. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 8.0%
Acetate Content (HPLC)	≤ 15.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.