Description

H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-Nh2 is a synthetic nonapeptide amide, a sequence derived from the C-terminal region of the cholecystokinin (CCK) family of peptides. This compound is of significant interest in biochemical and pharmacological research due to its role as a potent and selective ligand for the CCK-B/gastrin receptor subtype. It is primarily utilized by research institutions and pharmaceutical development companies focused on neuroscience, gastrointestinal physiology, and the development of receptor-targeted therapeutics.

Application

• Biochemical Research: Used as a high-affinity reference standard in receptor binding assays and signal transduction studies for the CCK-B receptor.
• Pharmacological Development: Serves as a critical tool compound for screening and characterizing novel CCK-B receptor antagonists or agonists in drug discovery pipelines.
• Neuroscience Studies: Employed in experimental models to investigate the role of CCK in anxiety, panic disorders, nociception, and memory processes.
• Gastrointestinal Research: Applied in studies exploring gastrin-mediated functions, such as gastric acid secretion and mucosal growth.
• Peptide Chemistry Reference: Acts as a benchmark for purity in analytical method development and quality control for synthetic peptide manufacturing.

Basic Information

Product Name	H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-Nh2
CAS No.	25679-24-7
Molecular Formula	C58H73N11O15S2
Molecular Weight	1220.4 g/mol
Synonyms	CCK-9; Cholecystokinin Nonapeptide; Sincalide (partial sequence analog); Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-NH2; CCK (26-34), amide; Gastrin/CCK-B Receptor Ligand; Nonapeptide CCK Fragment; BDNL
EINECS	Contact for details

Quality Control

Every batch of H-Asp-Tyr-Met-Gly-Trp-Met-Asp-Phe-Nh2 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the exacting standards required for research-grade bioactive peptides. A comprehensive Certificate of Analysis (COA), detailing results from HPLC, MS, and amino acid analysis, is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider keeping the product desiccated under an inert atmosphere. Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with theoretical molecular weight
Purity (HPLC)	≥ 95% (Area % at 214 nm)
Assay (Peptide Content)	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	Within ± 10% of theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.