Description

4-Fluoro-Dl-Tryptophan is a fluorinated derivative of the essential amino acid tryptophan, where a fluorine atom is substituted at the 4-position of the indole ring. This structural modification is crucial for probing biological systems, as it serves as a valuable non-natural amino acid in biochemical and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for applications in medicinal chemistry, proteomics, and as a building block for novel peptide-based therapeutics and diagnostic agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and neurology research.
• Biochemical Research: Used as a non-natural amino acid probe to study enzyme mechanisms, protein structure, and function through 19F NMR spectroscopy.
• Peptide Synthesis: Incorporated into custom peptides to enhance metabolic stability, alter binding affinity, or introduce fluorophores for imaging.
• Metabolic Pathway Studies: Employed to investigate tryptophan metabolism and the biosynthesis of serotonin and melatonin analogs.
• Agrochemical Research: Serves as a precursor in developing new crop protection agents with improved efficacy.
• Academic & Contract Research: Essential for basic research in universities and CROs (Contract Research Organizations) exploring fluorinated biomolecules.

Basic Information

Product Name	4-Fluoro-Dl-Tryptophan
CAS No.	25631-05-4
Molecular Formula	C11H11FN2O2
Molecular Weight	222.22 g/mol
Synonyms	DL-4-Fluorotryptophan; (±)-4-Fluorotryptophan; 4-Fluoro-DL-tryptophan; 4-FTrp; 4-FT; 2-Amino-3-(4-fluoro-1H-indol-3-yl)propanoic acid; 4-Fluoroindole-3-alanine; (RS)-4-Fluorotryptophan
EINECS	Contact for details

Quality Control

Our 4-Fluoro-Dl-Tryptophan is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.