Description

Lysinonorleucine is a non-proteinogenic amino acid derivative formed by the cross-linking of lysine residues, serving as a critical biomarker for oxidative stress and protein damage. This compound matters significantly for researchers and quality control professionals who require precise analytical standards to study advanced glycation end-products (AGEs) and connective tissue disorders. It is primarily needed by the pharmaceutical, diagnostic, and life science research industries for developing assays and investigating metabolic pathways related to diabetes and aging.

Application

• Biochemical Research: Used as a reference standard in the study of non-enzymatic collagen cross-links and protein aging.
• Diagnostic Development: Serves as a key calibrant for quantifying lysinonorleucine in biological samples (e.g., urine, tissue) to assess oxidative stress levels.
• Pharmaceutical Analysis: Employed in method development and validation for quality control of products related to metabolic diseases.
• Nutritional Science: Applied in research investigating the impact of diet and Maillard reaction products on human health.
• Material Science: Studied for its role in the properties of cross-linked biopolymers and biomaterials.

Basic Information

Product Name	Lysinonorleucine
CAS No.	25612-46-8
Molecular Formula	C12H26N4O4
Molecular Weight	290.36 g/mol
Synonyms	LNL; 5,5'-Diamino-2,2'-dihydroxy-6,6'-dimethyl-4,4'-diaza-n-heptanedioic Acid; 2,6-Diamino-7-hydroxy-7-methyloctanedioic Acid; (2S,2'S)-2,2'-Diaminosuberic Acid; Lysino-nor-leucine; AGE Biomarker; Oxidative Stress Marker
EINECS	Contact for details

Quality Control

Our Lysinonorleucine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and MS, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Assay	≥ 98.0% (on dried basis)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.