Description

Poly-L-Valine is a synthetic, high-purity homopolymer of the essential amino acid L-valine, widely recognized for its role in advanced material science and biomedical research. This compound is valued for its predictable secondary structure and biocompatibility, making it a critical building block for designing functional peptides and biomaterials. It serves as an indispensable raw material for researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors.

Application

• Biomedical Research & Peptide Synthesis: A fundamental component for constructing model peptides to study protein folding, stability, and structure-function relationships.
• Drug Delivery Systems: Used in the development of biodegradable polymeric carriers and hydrogels for controlled release of active pharmaceutical ingredients (APIs).
• Biomaterial Fabrication: Serves as a key monomer for creating synthetic polypeptides with tailored properties for tissue engineering scaffolds and implant coatings.
• Chiral Stationary Phases: Employed in the preparation of high-performance liquid chromatography (HPLC) columns for the separation of enantiomers in analytical and preparative scales.
• Surface Modification & Coatings: Utilized to engineer surfaces with specific bio-recognition or anti-fouling properties for diagnostic devices and biosensors.
• Reference Standard: Acts as a pure standard in analytical laboratories for method development, validation, and quality control of amino acid-based products.

Basic Information

Product Name	Poly-L-Valine
CAS No.	25609-85-2
Molecular Formula	(C5H9NO)n
Molecular Weight	Variable (based on degree of polymerization)
Synonyms	Poly(L-valine); L-Valine Homopolymer; PVal; PVAL; Poly(valine); (S)-Poly(valine); Poly-[(S)-2-amino-3-methylbutanoic acid]; NSC 334365
EINECS	Contact for details

Quality Control

Our Poly-L-Valine is manufactured under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including determination of molecular weight distribution, enantiomeric purity, and residual solvent analysis, to ensure it meets stringent research and production standards. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (Amino Acid Analysis)	≥ 95.0%
Specific Rotation [α]D20	Contact for details
Molecular Weight (Average)	Customizable (e.g., 1k - 20k Da)
Moisture Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.