Description

Threonine, 2-Methyl- (9Ci) is a specialized amino acid derivative with a distinct methyl substitution on the threonine backbone. This structural modification makes it a valuable chiral building block and intermediate for advanced organic synthesis and pharmaceutical research. It is particularly relevant for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical sectors who require high-purity, non-natural amino acids for developing novel compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for peptidomimetics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators that incorporate amino acid motifs for enhanced bioactivity.
• Biochemical Research: Acts as a substrate analog or inhibitor in enzymatic studies and metabolic pathway investigations within life science research.
• Peptide Chemistry: Employed in solid-phase and solution-phase peptide synthesis to introduce structural diversity and modulate the physicochemical properties of synthetic peptides.
• Fine Chemical Production: Functions as a versatile intermediate for synthesizing complex organic molecules, including specialty surfactants and ligands for catalysis.
• Nutritional Science Studies: Used in metabolic and nutritional research to study the effects of modified amino acids on biological systems.

Basic Information

Product Name	Threonine, 2-Methyl- (9Ci)
CAS No.	25580-38-5
Molecular Formula	C5H11NO3
Molecular Weight	133.15 g/mol
Synonyms	2-Methylthreonine; (2S,3S)-2-Amino-3-hydroxy-2-methylbutanoic acid; allo-2-Methylthreonine; 3-Hydroxy-2-methyl-2-aminobutanoic acid; 2-Amino-3-hydroxy-2-methylbutyric acid; α-Methyl-threonine; 2-Methyl-threonine
EINECS	Contact for details

Quality Control

Our Threonine, 2-Methyl- (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% de (by chiral HPLC)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.