Description

n-(5-Oxo-L-Prolyl)-L-Histidinohydrazide is a high-purity, specialized peptide derivative with significant relevance in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block or intermediate in the synthesis of more complex bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide chemistry, drug discovery, and the development of novel therapeutic agents. Its specific structure makes it valuable for creating targeted molecular libraries and studying enzyme-substrate interactions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel peptide-based drugs and therapeutic candidates.
• Biochemical Research: Used as a standard or reagent in studies involving enzyme inhibition, receptor binding assays, and proteomics.
• Peptide Library Synthesis: Employed in combinatorial chemistry for the generation of diverse peptide libraries for high-throughput screening.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic chemistry and medicinal chemistry projects.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.

Basic Information

Product Name	n-(5-Oxo-L-Prolyl)-L-Histidinohydrazide
CAS No.	25575-89-7
Molecular Formula	C11H16N6O3
Molecular Weight	280.29 g/mol
Synonyms	L-Histidine, N2-[(5-oxo-L-prolyl)]-, hydrazide; L-Histidine, N-[(5-oxo-L-prolyl)]-, hydrazide; 5-Oxo-L-prolyl-L-histidinohydrazide; (S)-2-(2-((S)-5-Oxopyrrolidine-2-carboxamido)-3-(1H-imidazol-4-yl)propanoyl)hydrazine; N-[(5-Oxo-L-prolyl)]-L-histidinohydrazide; L-Histidinamide, N-[(5-oxo-L-prolyl)]-; Pro-His-NHNH2 (derivative)
EINECS	Contact for details

Quality Control

Our n-(5-Oxo-L-Prolyl)-L-Histidinohydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.