Description

Ribostamycin Sulfate Salt is a semi-synthetic aminoglycoside antibiotic derived from Streptomyces ribosidificus. This compound is valued for its broad-spectrum antibacterial activity, particularly against Gram-negative bacteria, making it a critical intermediate and active ingredient in pharmaceutical manufacturing. It is essential for research and production in the pharmaceutical, biotechnology, and veterinary medicine sectors, where reliable quality and consistent potency are paramount.

Application

• Pharmaceutical Active Ingredient: Used in the formulation of injectable antibiotic preparations for human and veterinary use.
• Biochemical Research: Serves as a key reagent in microbiological studies, antibiotic resistance research, and mechanism of action investigations.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, and microbiological assays.
• Veterinary Medicine: A component in treatments for bacterial infections in livestock and companion animals.
• Cell Culture Applications: Used in selective media in biotechnology for the cultivation of specific cell lines.

Basic Information

Product Name	Ribostamycin Sulfate Salt
CAS No.	25546-65-0
Molecular Formula	C17H34N4O10 • xH2SO4
Molecular Weight	454.48 g/mol (base)
Synonyms	Ribostamycin Sulphate; Ribostamycin Sulfate; Antibiotic SF 733; Vistamycin Sulfate; Ribostamycin Hemisulfate; O-2,6-Diamino-2,6-dideoxy-α-D-glucopyranosyl-(1→4)-O-[β-D-ribofuranosyl-(1→5)]-2-deoxy-D-streptamine Sulfate; Antibiotic 2230
EINECS	Contact for details

Quality Control

Our Ribostamycin Sulfate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for related substances, residual solvents, and microbiological load. A detailed Certificate of Analysis (COA) is provided with each shipment to ensure compliance with relevant pharmaceutical and research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC, anhydrous basis)	≥ 95.0%
Water Content (KF)	≤ 5.0%
pH (1% solution)	4.0 - 6.0
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm
Bacterial Endotoxins	< 1.0 EU/mg (if applicable)
Microbial Enumeration	Meets Ph. Eur. 2.6.12/ USP <61>

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.