Description

3-Mercapto-L-Valine Hydrochloride is a high-purity, sulfur-containing amino acid derivative essential for advanced pharmaceutical synthesis and biochemical research. This compound serves as a critical chiral building block and a versatile precursor for introducing thiol functionality into complex molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for applications ranging from drug development to peptide modification.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Peptide Synthesis & Modification: Used to incorporate thiol groups into peptide chains, enabling site-specific conjugation, cyclization, or the formation of disulfide bonds for structural stabilization.
• Bioconjugation & Probe Development: Serves as a linker or functional handle for attaching fluorescent dyes, biotin, or other probes to biomolecules in diagnostic and research applications.
• Chemical Biology Research: Employed in studying enzyme mechanisms, protein interactions, and redox biology due to its reactive thiol moiety.
• Ligand for Catalyst Design: Used in the development of chiral ligands and catalysts for asymmetric synthesis in fine chemical production.
• Reference Standard: Sourced as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	3-Mercapto-L-Valine Hydrochloride
CAS No.	25526-04-9
Molecular Formula	C5H12ClNO2S
Molecular Weight	185.67 g/mol
Synonyms	L-Valine, 3-mercapto-, hydrochloride (1:1); (2S)-2-Amino-3-mercapto-3-methylbutanoic acid hydrochloride; 3-Mercaptovaline HCl; 3-Thio-L-valine hydrochloride; (S)-2-Amino-3-mercapto-3-methylbutyric acid hydrochloride; 3-Methyl-2-amino-3-mercaptobutyric acid hydrochloride; 3-Mercapto-DL-valine hydrochloride (related); NSC 334910
EINECS	Contact for details

Quality Control

Our 3-Mercapto-L-Valine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets stringent specifications for research and GMP-grade applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its hygroscopic and easily oxidized nature. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.