Description

Ammonium 5-Oxo-L-Prolinate is the ammonium salt of the amino acid derivative 5-oxoproline. This compound is valued for its role as a key intermediate in the synthesis of bioactive molecules and as a building block in pharmaceutical research and development. It is primarily utilized by manufacturers and R&D laboratories in the pharmaceutical, nutraceutical, and fine chemical sectors seeking high-purity chiral intermediates.

Application

• Pharmaceutical Intermediate: A crucial chiral building block for the synthesis of various active pharmaceutical ingredients (APIs) and prodrugs.
• Biochemical Research: Used in enzymatic studies and metabolic pathway research related to glutathione synthesis and the γ-glutamyl cycle.
• Peptide Synthesis: Serves as a protected form of glutamic acid or as a specialized precursor in solid-phase and solution-phase peptide chemistry.
• Nutraceutical Formulation: Investigated for use in dietary supplements targeting cellular antioxidant systems.
• Cosmetic Ingredients: Potential application in skincare formulations for its moisturizing and cell-renewal properties.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC or LC-MS methods.

Basic Information

Product Name	Ammonium 5-Oxo-L-Prolinate
CAS No.	25501-47-7
Molecular Formula	C5H10N2O3 • xNH3 (Contact for exact stoichiometry)
Molecular Weight	Contact for details
Synonyms	L-Pyroglutamic Acid Ammonium Salt; Ammonium L-Pyroglutamate; 5-Oxo-L-proline Ammonium Salt; Ammonium (S)-5-Oxopyrrolidine-2-carboxylate; L-2-Pyrrolidone-5-carboxylic Acid Ammonium Salt; PCA Ammonium Salt; Ammonium PCA; Glutamic Acid Lactam Ammonium Salt
EINECS	Contact for details

Quality Control

Our Ammonium 5-Oxo-L-Prolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, chiral purity, and impurity profiles. Specifications can be tailored to meet pharmaceutical (GMP) or research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption. Recommended long-term storage at controlled room temperature (15-25°C).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.