Description

3-Amino-4-Methylbenzotrifluoride is a versatile fluorinated aromatic amine building block of significant industrial importance. Its trifluoromethyl and amino functional groups make it a critical intermediate for synthesizing advanced materials and active pharmaceutical ingredients (APIs). This compound is essential for manufacturers in the agrochemical, pharmaceutical, and specialty chemical sectors seeking to develop novel compounds with enhanced properties.

Application

• Agrochemical Intermediates: A key precursor for the synthesis of advanced herbicides, fungicides, and insecticides, leveraging the trifluoromethyl group for improved bioactivity and environmental stability.
• Pharmaceutical Synthesis: Serves as a crucial building block in the development of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs.
• Dye and Pigment Manufacturing: Used in the production of specialized dyes, pigments, and optical brighteners where the amino group facilitates coupling reactions.
• Liquid Crystal and OLED Materials: An important intermediate for creating fluorinated components in electronic display materials and organic light-emitting diodes (OLEDs).
• Polymer Modifiers: Employed to introduce fluorine-containing side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Buchwald-Hartwig amination) for creating complex biaryl structures.

Basic Information

Product Name	3-Amino-4-Methylbenzotrifluoride
CAS No.	25449-96-1
Molecular Formula	C8H8F3N
Molecular Weight	175.15 g/mol
Synonyms	2-Amino-α,α,α-trifluoro-p-xylene; 4-Methyl-3-(trifluoromethyl)aniline; 3-Amino-4-methyl-α,α,α-trifluorotoluene; 3-Amino-4-methylbenzotrifluoride; 3-Trifluoromethyl-4-methylaniline; 4-Methyl-3-trifluoromethylaniline; 2-Methyl-5-(trifluoromethyl)aniline; 5-Amino-2-methylbenzotrifluoride
EINECS	Contact for details

Quality Control

Our 3-Amino-4-Methylbenzotrifluoride is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for critical applications in pharmaceutical and agrochemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Light yellow to brown crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	40 - 44 °C
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.