Description

Poly(Glycyl-Prolyl-Serine) is a synthetic polypeptide composed of the amino acid sequence glycine, proline, and serine. This compound is significant for its role as a model substrate and building block in biochemical research, particularly in studies of collagen structure, enzyme kinetics, and peptide synthesis. It is primarily needed by research institutions, pharmaceutical R&D departments, and biotechnology companies focused on connective tissue biology, protease activity, and advanced biomaterial development.

Application

• Biochemical Research: Used as a standardized substrate for studying the activity and specificity of proteolytic enzymes, particularly collagenases and other matrix metalloproteinases (MMPs).
• Collagen Mimetics: Serves as a model peptide in research investigating collagen structure, stability, and self-assembly due to its repeating (Gly-Pro-Ser)n sequence.
• Pharmaceutical Development: Employed in drug discovery programs targeting fibrosis, wound healing, and diseases involving extracellular matrix remodeling.
• Biomaterial Science: Acts as a component in the design and testing of novel bioactive hydrogels, scaffolds, and coatings for tissue engineering applications.
• Enzyme Assay Kits: Incorporated into commercial and in-house assay kits for quantifying enzyme activity in diagnostic and research settings.
• Peptide Synthesis Standard: Used as a reference standard or intermediate in solid-phase and solution-phase peptide synthesis to validate coupling efficiency and purification methods.

Basic Information

Product Name	Poly(Glycyl-Prolyl-Serine)
CAS No.	25249-76-7
Molecular Formula	(C11H17N3O5)n
Molecular Weight	Contact for details (Polymer)
Synonyms	Poly(Gly-Pro-Ser); (Gly-Pro-Ser)n; Poly(Glycyl-L-Prolyl-L-Serine); Poly(GPS); Glycylprolylserine Polymer; Poly[Glycyl(2S)-Prolyl(2S)-Serine]; L-Glycyl-L-Prolyl-L-Serine Homopolymer; Collagen Model Peptide (Gly-Pro-Ser)n
EINECS	Contact for details

Quality Control

Our Poly(Glycyl-Prolyl-Serine) is produced under controlled conditions to ensure batch-to-batch consistency for research applications. Each lot undergoes rigorous analytical testing, including sequence verification and purity assessment. A comprehensive Certificate of Analysis (COA) detailing specific parameters such as average molecular weight, amino acid composition, and purity is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Allow the sealed container to equilibrate to room temperature before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Sequence	(Gly-Pro-Ser)n
Average Molecular Weight	As per customer requirement
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.