Description

4-Hydroxy-L-Tryptophan is a naturally occurring amino acid derivative and a key metabolic intermediate in the biosynthesis of serotonin and melatonin. This compound matters for its role as a direct precursor in neurotransmitter synthesis, offering significant value in research and development for neurological and metabolic pathways. It is primarily needed by manufacturers in the pharmaceutical, nutraceutical, and advanced biochemical research sectors for applications in dietary supplements, clinical research, and as a high-purity reference standard.

Application

• Pharmaceutical intermediate for serotonin-related drug development and synthesis.
• Active ingredient in dietary supplements targeting mood, sleep, and cognitive support.
• Biochemical research standard for studying neurotransmitter biosynthesis and metabolic disorders.
• Precursor in the synthesis of more complex neuroactive compounds and alkaloids.
• Reference material for analytical method development and quality control in pharmaceutical labs.
• Raw material for advanced nutraceutical formulations requiring high-purity amino acid derivatives.

Basic Information

Product Name	4-Hydroxy-L-Tryptophan
CAS No.	25242-90-4
Molecular Formula	C11H12N2O3
Molecular Weight	220.23 g/mol
Synonyms	L-4-Hydroxytryptophan; 5-Hydroxy-L-tryptophan (common misnomer); Oxitriptan; L-5-HTP; 5-HTP; 5-Hydroxytryptophan; 3-(5-Hydroxy-1H-indol-3-yl)-L-alanine; 5-Hydroxy-L-tryptophan; 5-Hydroxy-DL-tryptophan (racemic mixture); 5-HTP (abbreviation)
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-L-Tryptophan is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for research and production use. Certificates of Analysis (COA) detailing specific results for assay, impurities, and other critical parameters are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Specific Rotation	-30.0° to -34.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.