Description

Pyrimidine, 5-(Bromomethyl)- (8Ci,9Ci) is a versatile brominated pyrimidine derivative, a crucial building block in advanced organic synthesis. Its reactive bromomethyl group makes it an essential intermediate for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. This high-purity compound is primarily sought by R&D chemists and process development scientists in the life sciences and fine chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of nucleoside analogs, kinase inhibitors, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators, leveraging the pyrimidine core's bioactivity.
• Chemical Biology & Proteomics: Serves as a versatile linker or functionalization agent for bioconjugation, probe development, and protein labeling studies.
• Material Science Research: Building block for creating functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic and halogenated properties.
• Cross-Coupling Reactions: Valuable substrate in palladium-catalyzed reactions (e.g., Suzuki, Heck) for introducing the pyrimidine moiety into more complex systems.
• Academic & Contract Research: Essential reagent for methodological development in organic chemistry and medicinal chemistry programs at universities and CROs.

Basic Information

Item	Details
Product Name	Pyrimidine, 5-(Bromomethyl)- (8Ci,9Ci)
CAS No.	25198-96-3
Molecular Formula	C5H5BrN2
Molecular Weight	173.01 g/mol
Synonyms	5-(Bromomethyl)pyrimidine; 5-Bromomethylpyrimidine; (Bromomethyl)pyrimidine; Pyrimidine, 5-(bromomethyl)-; NSC 401564; 2,4-Pyrimidinedimethanol, 5-bromo-? (tautomer); AI3-52021
EINECS	Contact for details

Quality Control

Every batch of Pyrimidine, 5-(Bromomethyl)- is produced and tested under a strict quality management system. We provide comprehensive analytical data to ensure the compound meets the high-purity standards required for research and development. A Certificate of Analysis (COA) detailing purity (typically by HPLC/NMR), identity confirmation, and impurity profile is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and degradation. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.