Description

5-Methoxy-L-Tryptophan is a specialized, non-proteinogenic derivative of the essential amino acid L-tryptophan, distinguished by a methoxy substitution on the indole ring. This structural modification grants it unique biochemical properties, making it a valuable advanced pharmaceutical intermediate and a critical building block in research. It is primarily sought after by manufacturers and research institutions in the pharmaceutical, biotechnology, and nutraceutical sectors for developing novel therapeutic agents and studying metabolic pathways.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug molecules, particularly those targeting neurological and metabolic disorders.
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and neurotransmitter research.
• Nutraceutical Development: Investigated for potential applications in advanced dietary supplements due to its role as a modified amino acid.
• Peptide Synthesis: Serves as a specialized building block for incorporating modified tryptophan residues into synthetic peptides and peptidomimetics.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR method development and validation.

Basic Information

Product Name	5-Methoxy-L-Tryptophan
CAS No.	25197-96-0
Molecular Formula	C₁₂H₁₄N₂O₃
Molecular Weight	234.25 g/mol
Synonyms	L-5-Methoxytryptophan; (S)-2-Amino-3-(5-methoxy-1H-indol-3-yl)propanoic acid; 5-Methoxy-L-tryptophan; 5-Methoxy-L-Trp; 5-MeO-L-Trp; 5-Methoxytryptophan; 5-Methoxy-DL-tryptophan (for the racemic mixture)
EINECS	Contact for details

Quality Control

Our 5-Methoxy-L-Tryptophan is produced under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, chiral purity, and impurity profiles. While we offer standard research and technical grades, our processes are designed to meet the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-Isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.