Description

Poly-γ-Ethyl L-Glutamate is a synthetic polypeptide derivative of L-glutamic acid, where the γ-carboxyl group is esterified with ethanol. This compound matters as a versatile, biocompatible building block for advanced biomaterials and controlled-release systems. It is primarily needed by researchers and manufacturers in the pharmaceutical, biomedical engineering, and specialty polymer sectors for applications ranging from drug delivery to tissue scaffolding.

Application

• Biomedical Research: As a model polypeptide for studying protein folding, enzyme interactions, and biocompatibility.
• Drug Delivery Systems: A key component in the synthesis of biodegradable microspheres, nanoparticles, and hydrogels for controlled and targeted release of active pharmaceutical ingredients (APIs).
• Tissue Engineering: Used to create scaffolds that support cell growth and tissue regeneration due to its tunable degradation profile and structural properties.
• Specialty Polymers: Serves as a precursor for synthesizing functional polymers with specific chiral, mechanical, or surface properties.
• Cosmetic Formulations: Employed in advanced skincare products for its film-forming and moisture-retention capabilities.
• Analytical Standards: Used as a reference standard in chromatographic analysis and quality control within pharmaceutical laboratories.

Basic Information

Product Name	Poly-γ-Ethyl L-Glutamate
CAS No.	25189-52-0
Molecular Formula	(C7H11NO4)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly(γ-ethyl L-glutamate); PGEG; PELG; Poly(glutamic acid ethyl ester); L-Glutamic acid, γ-ethyl ester, homopolymer; Poly(ethyl L-glutamate); γ-Ethyl L-glutamate polymer; Poly(GE)
EINECS	Contact for details

Quality Control

Our Poly-γ-Ethyl L-Glutamate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure consistency in molecular weight distribution, purity, and functional performance. Certificates of Analysis (COA) detailing specifications such as degree of polymerization, residual solvent levels, and chiral purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Molecular Weight (GPC)	Specified range available
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.