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(2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(2-Hydroxypropanoylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid CAS NO 25138-66-3


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CAS No.:25138-66-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(2-Hydroxypropanoylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid is a complex, high-purity chiral compound of significant interest in advanced pharmaceutical research and development. Its intricate molecular structure, featuring multiple functional groups including amino, carboxy, and thioester moieties, makes it a valuable building block for peptide mimetics and enzyme inhibitor synthesis. This chemical is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in creating novel therapeutic agents, particularly in areas targeting specific enzymatic pathways.

Application

  • Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, especially protease inhibitors and other enzyme-targeted therapies.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate reaction mechanisms and kinetics.
  • Peptidomimetic Development: Serves as a sophisticated building block for constructing complex peptide analogs with enhanced stability and bioavailability.
  • Ligand Synthesis for Catalysis: Potential use in creating specialized ligands for asymmetric catalysis in fine chemical production.
  • Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Item Details
Product Name (2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(2-Hydroxypropanoylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid
CAS No. 25138-66-3
Molecular Formula C13H21N3O8S
Molecular Weight 379.39 g/mol
Synonyms N-[(R)-1-[(Carboxymethyl)carbamoyl]-2-[(2-hydroxypropanoyl)sulfanyl]ethyl]-L-glutamine; L-Glutamine, N-[(1R)-1-[(carboxymethyl)amino]-1-oxo-2-[(2-hydroxy-1-oxopropyl)thio]ethyl]-; (2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(2-hydroxypropanoylsulfanyl)ethyl]carbamoyl]butanoic acid; Glutamine derivative CAS 25138-66-3; Thioester-linked glutamine analog; N-Carbamoylmethyl-N'-[(R)-2-mercapto-1-(2-hydroxypropanoyl)ethyl]-L-glutamine diamide
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Quality Control

Our (2S)-2-Amino-4-[[(1R)-1-(Carboxymethylcarbamoyl)-2-(2-Hydroxypropanoylsulfanyl)Ethyl]Carbamoyl]Butanoic Acid is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, chiral analysis, and identity confirmation to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Chiral Purity ≥ 99.0% ee
Water Content (KF) ≤ 2.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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