Description

Poly-D-Glutamic Acid is a high-purity, synthetic polymer composed of D-glutamic acid monomers. This unique stereochemistry offers distinct advantages in applications requiring resistance to enzymatic degradation, enhancing stability and performance. It is a critical material for researchers and manufacturers in the pharmaceutical, biomedical, and advanced materials sectors seeking reliable, high-quality biopolymers.

Application

• Drug Delivery Systems: As a biodegradable and biocompatible carrier for controlled release formulations, particularly for sensitive active pharmaceutical ingredients (APIs).
• Biomedical Research: Used in the development of hydrogels, tissue engineering scaffolds, and other biomaterials due to its tunable properties.
• Cosmetic Formulations: Serves as a high-performance moisturizing agent and film-former in skincare products, leveraging its humectant properties.
• Enzyme Studies: Acts as a stable, non-hydrolyzable substrate or inhibitor in biochemical and enzymatic research.
• Industrial Biotechnology: Potential use in the synthesis of specialty chemicals and as a component in advanced material science applications.

Basic Information

Product Name	Poly-D-Glutamic Acid
CAS No.	25104-13-6
Molecular Formula	(C5H7NO3)n
Molecular Weight	Varies (Polymer)
Synonyms	D-Polyglutamic Acid; Poly(D-glutamic acid); PGA (D-form); PDGA; (D)-Poly-α-glutamic Acid; Poly(imino(1-carboxy-4-oxo-1,4-butanediyl)); γ-Poly-D-glutamic Acid; Poly-γ-D-glutamate
EINECS	Contact for details

Quality Control

Our Poly-D-Glutamic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing key parameters such as molecular weight distribution, enantiomeric purity, and residual solvents are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area. Due to its hygroscopic nature, the container should be kept sealed under dry, inert conditions to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Enantiomeric Purity	≥ 98.0% D-isomer
Molecular Weight (Avg.)	Specified range available (e.g., 5k-50k Da)
Loss on Drying	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.