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Poly-γ-Benzyl L-Glutamate CAS NO 25014-27-1
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CAS No.:25014-27-1
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Poly-γ-Benzyl L-Glutamate is a synthetic polypeptide derived from the amino acid L-glutamic acid, where the γ-carboxyl group is protected by a benzyl ester. This compound matters as a key intermediate and model polymer in advanced materials research, particularly for studying polypeptide conformation and self-assembly. It is primarily needed by researchers and manufacturers in the pharmaceutical, biomedical, and specialty polymer industries for applications ranging from drug delivery systems to the development of biomimetic materials.
Application
- Biomedical Research: As a model compound for studying α-helix and β-sheet conformations of polypeptides.
- Drug Delivery Systems: A precursor or building block for designing biodegradable polymeric carriers for controlled drug release.
- Tissue Engineering: Used in the fabrication of scaffolds that mimic the extracellular matrix due to its polypeptide structure.
- Specialty Polymers: Serves as an intermediate in the synthesis of polyglutamic acid (PGA) and other functional polymers.
- Surface Modification: Employed to create bioactive or specific-interaction coatings on medical devices and implants.
- Material Science Studies: Investigated for its liquid crystalline properties and potential in creating ordered polymeric materials.
Basic Information
| Item | Details |
|---|---|
| Product Name | Poly-γ-Benzyl L-Glutamate |
| CAS No. | 25014-27-1 |
| Molecular Formula | (C12H13NO4)n |
| Molecular Weight | ~235.24 (monomer unit) |
| Synonyms | Poly(γ-benzyl L-glutamate); PBLG; Poly(benzyl L-glutamate); γ-Benzyl L-glutamate polymer; L-Glutamic acid, γ-benzyl ester, homopolymer; Benzyl L-glutamate polymer; Poly(Bzl-L-Glu); PBG |
| EINECS | Contact for details |
Quality Control
Our Poly-γ-Benzyl L-Glutamate is produced under controlled conditions to ensure batch-to-batch consistency. Quality is assured through rigorous analytical testing, including determination of molecular weight distribution, optical rotation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing purity, specific rotation, and other critical parameters is provided with each shipment to support your research and development requirements.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect the material's properties.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or solid |
| Identification (IR) | Conforms to structure |
| Specific Rotation [α] | Contact for details |
| Purity (HPLC) | > 95% |
| Molecular Weight (GPC) | Specified range available (e.g., 10k-100k Da) |
| Moisture Content (KF) | < 2.0% |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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