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Poly-γ-Benzyl L-Glutamate CAS NO 25014-27-1


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CAS No.:25014-27-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Poly-γ-Benzyl L-Glutamate is a synthetic polypeptide derived from the amino acid L-glutamic acid, where the γ-carboxyl group is protected by a benzyl ester. This compound matters as a key intermediate and model polymer in advanced materials research, particularly for studying polypeptide conformation and self-assembly. It is primarily needed by researchers and manufacturers in the pharmaceutical, biomedical, and specialty polymer industries for applications ranging from drug delivery systems to the development of biomimetic materials.

Application

  • Biomedical Research: As a model compound for studying α-helix and β-sheet conformations of polypeptides.
  • Drug Delivery Systems: A precursor or building block for designing biodegradable polymeric carriers for controlled drug release.
  • Tissue Engineering: Used in the fabrication of scaffolds that mimic the extracellular matrix due to its polypeptide structure.
  • Specialty Polymers: Serves as an intermediate in the synthesis of polyglutamic acid (PGA) and other functional polymers.
  • Surface Modification: Employed to create bioactive or specific-interaction coatings on medical devices and implants.
  • Material Science Studies: Investigated for its liquid crystalline properties and potential in creating ordered polymeric materials.

Basic Information

Item Details
Product Name Poly-γ-Benzyl L-Glutamate
CAS No. 25014-27-1
Molecular Formula (C12H13NO4)n
Molecular Weight ~235.24 (monomer unit)
Synonyms Poly(γ-benzyl L-glutamate); PBLG; Poly(benzyl L-glutamate); γ-Benzyl L-glutamate polymer; L-Glutamic acid, γ-benzyl ester, homopolymer; Benzyl L-glutamate polymer; Poly(Bzl-L-Glu); PBG
EINECS Contact for details

Quality Control

Our Poly-γ-Benzyl L-Glutamate is produced under controlled conditions to ensure batch-to-batch consistency. Quality is assured through rigorous analytical testing, including determination of molecular weight distribution, optical rotation, and residual solvent analysis. A comprehensive Certificate of Analysis (COA) detailing purity, specific rotation, and other critical parameters is provided with each shipment to support your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect the material's properties.

Specification

Item Specification
Appearance White to off-white powder or solid
Identification (IR) Conforms to structure
Specific Rotation [α] Contact for details
Purity (HPLC) > 95%
Molecular Weight (GPC) Specified range available (e.g., 10k-100k Da)
Moisture Content (KF) < 2.0%
Residual Solvents (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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