Description

Z-Gly-Leu-Ala-OH CAS NO 24960-20-1 is a protected tripeptide derivative, serving as a crucial building block in solid-phase peptide synthesis (SPPS). This compound is valued for its role in constructing specific peptide sequences for research and development. It is primarily utilized by pharmaceutical researchers, biochemists, and fine chemical manufacturers involved in peptide-based drug discovery and biochemical studies.

Application

• Peptide Synthesis Intermediate: A key protected fragment for the controlled assembly of longer, complex peptide chains in solid-phase or solution-phase synthesis.
• Pharmaceutical Research: Used in the R&D of novel therapeutic peptides targeting various diseases, where the Gly-Leu-Ala sequence may confer specific biological activity.
• Biochemical Tool Development: Employed in the synthesis of enzyme substrates, inhibitors, or standards for proteomics and metabolic studies.
• Custom Peptide Production: A fundamental component for contract research organizations (CROs) and manufacturers producing custom peptides for clients.
• Academic Research: Utilized in university and institutional labs for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Z-Gly-Leu-Ala-OH
CAS No.	24960-20-1
Molecular Formula	C₂₂H₃₁N₃O₇
Molecular Weight	449.50 g/mol
Synonyms	Z-Gly-Leu-Ala; N-Carbobenzoxy-glycyl-L-leucyl-L-alanine; N-Cbz-Glycyl-L-leucyl-L-alanine; Cbz-Gly-Leu-Ala-OH; Benzyloxycarbonyl-glycyl-L-leucyl-L-alanine; (S)-2-(((S)-1-((((Benzyloxy)carbonyl)amino)methyl)-2-methyl-1-oxopropan-2-yl)amino)-1-hydroxy-4-methylpentan-1-one; Z-Gly-L-Leu-L-Ala-OH; CBZ-Gly-Leu-Ala
EINECS	Contact for details

Quality Control

Our Z-Gly-Leu-Ala-OH is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and synthesis applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and residual solvent levels is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.