Description

Z-Ala-Leu-Oh is a protected dipeptide derivative, specifically the benzyloxycarbonyl (Z) protected form of the alanine-leucine dipeptide with a free carboxylic acid. This compound serves as a crucial building block in solid-phase and solution-phase peptide synthesis, enabling the controlled elongation of peptide chains. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and life sciences sectors for developing novel therapeutic peptides and biochemical probes.

Application

• Peptide Synthesis Intermediate: A key raw material for the controlled assembly of custom peptide sequences in research and development.
• Pharmaceutical Active Pharmaceutical Ingredient (API) Development: Used in the research and scale-up synthesis of peptide-based drug candidates.
• Biochemical Research: Employed in studies of enzyme substrates, inhibitors, and protein-protein interactions.
• Protecting Group Chemistry: Serves as a model compound for studying Z-group (Cbz) protection and deprotection strategies.
• Reference Standard: Used as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Product Name	Z-Ala-Leu-Oh
CAS No.	24959-68-0
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	N-Carbobenzoxy-L-alanyl-L-leucine; Cbz-Ala-Leu-OH; Z-L-Ala-L-Leu-OH; N-(Benzyloxycarbonyl)-L-alanyl-L-leucine; Nα-Cbz-L-alanyl-L-leucine; (2S)-2-[[(2S)-2-[(Benzyloxy)carbonylamino]propanoyl]amino]-4-methylpentanoic acid; CBZ-ALA-LEU; Z-A-L-OH
EINECS	Contact for details

Quality Control

Every batch of Z-Ala-Leu-Oh is produced and tested under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity (by HPLC), chiral purity, and identity confirmation is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-L isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.