Description

N,n-Dimethyl-His-Oh CAS NO 24940-57-6 is a specialized histidine derivative, a key intermediate in advanced organic synthesis and pharmaceutical research. This compound is valued for its role in modifying peptide structures and creating novel bioactive molecules. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing new therapeutic agents and biochemical tools.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used in proteomics and enzymology studies to investigate protein structure-function relationships and enzyme mechanisms.
• Peptide Modification: Serves as a precursor for introducing dimethylated histidine analogs into synthetic peptides to alter their biological activity and stability.
• Ligand Synthesis: Employed in the development of specialized chelating agents and catalysts for metal-ion coordination chemistry.
• Reference Standard: Acts as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	N,n-Dimethyl-His-Oh
CAS No.	24940-57-6
Molecular Formula	C8H15N3O2
Molecular Weight	185.22 g/mol
Synonyms	N,N-Dimethyl-L-histidine; 3-(1H-Imidazol-4-yl)-2-(dimethylamino)propanoic acid; L-Histidine, N,N-dimethyl-; (2S)-2-(Dimethylamino)-3-(1H-imidazol-5-yl)propanoic acid; N(τ)-Methylhistidine derivative; DMH; N,N-Dimethylhistidine
EINECS	Contact for details

Quality Control

Our N,n-Dimethyl-His-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets exacting standards for research and synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation and absorption of moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.