Description

3-(Difluoro-Methanesulfonyl)-Phenylamine is a specialized aromatic amine derivative featuring a difluoromethanesulfonyl substituent, making it a valuable fluorinated building block for advanced synthesis. This compound is critical for introducing unique electronic and steric properties into target molecules, enabling the development of novel materials and active ingredients. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating next-generation compounds with enhanced performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms can improve metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and as a building block for functional materials.
• Organic Electronic Materials: Employed in the synthesis of novel monomers and polymers for applications in organic light-emitting diodes (OLEDs) and semiconductors.
• Fluorinated Surfactant Research: Acts as an intermediate in the development of specialty surfactants and surface modifiers with unique properties.
• Custom Synthesis and Contract Manufacturing: Supplied to custom synthesis firms and CDMOs (Contract Development and Manufacturing Organizations) for client-specific R&D projects.

Basic Information

Product Name	3-(Difluoro-Methanesulfonyl)-Phenylamine
CAS No.	24906-76-1
Molecular Formula	C7H7F2NO2S
Molecular Weight	207.20 g/mol
Synonyms	3-Aminophenyl difluoromethyl sulfone; 3-(Difluoromethylsulfonyl)aniline; Benzenamine, 3-[(difluoromethyl)sulfonyl]-; 3-(Difluoromethanesulfonyl)aniline; 3-(Difluoromethylsulfonyl)phenylamine; 1-Amino-3-(difluoromethylsulfonyl)benzene; m-(Difluoromethylsulfonyl)aniline
EINECS	Contact for details

Quality Control

Our 3-(Difluoro-Methanesulfonyl)-Phenylamine is produced under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment. We adhere to cGMP guidelines where applicable to support our clients in regulated industry segments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary. Keep away from strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.