Description

4-Chloro-5,6,7,8-tetrahydro-benzo[4,5]furo[2,3-d]pyrimidine is a high-value, heterocyclic organic compound belonging to the fused pyrimidine class, serving as a critical building block in advanced chemical synthesis. Its unique molecular architecture makes it an indispensable key intermediate for the research and development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular frameworks.

Application

• Pharmaceutical Intermediate: A versatile scaffold for synthesizing potential drug candidates, particularly in oncology, CNS disorders, and antiviral research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive pyrimidine core.
• Chemical Biology Probe: Serves as a core structure for designing molecular probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and advanced polymers.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Chloro-5,6,7,8-tetrahydro-benzo[4,5]furo[2,3-d]pyrimidine
CAS No.	24889-36-9
Molecular Formula	C₁₀H₉ClN₂O
Molecular Weight	208.65 g/mol
Synonyms	4-Chloro-5,6,7,8-tetrahydrobenzo[4,5]furo[2,3-d]pyrimidine; 4-Chloro-5,6,7,8-tetrahydro-2H-benzo[4,5]furo[2,3-d]pyrimidine; 24889-36-9; Benzo[4,5]furo[2,3-d]pyrimidine, 4-chloro-5,6,7,8-tetrahydro-; 4-Chloro-5,6,7,8-tetrahydro-2H-1-benzofuro[2,3-d]pyrimidine
EINECS	Contact for details

Quality Control

Our production of 4-Chloro-5,6,7,8-tetrahydro-benzo[4,5]furo[2,3-d]pyrimidine adheres to stringent in-process controls and final batch release testing to ensure consistent purity and identity. Every lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.