Description

Cycloglutamate CAS NO 24885-60-7 is a specialized cyclic derivative of glutamic acid, offering unique structural and functional properties for advanced chemical synthesis. This compound is valued for its role as a versatile chiral building block and intermediate in the development of complex organic molecules. It is particularly relevant for research and production within the pharmaceutical, agrochemical, and fine chemical industries, where precise molecular architecture is critical.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), including potential neuroactive compounds and enzyme inhibitors.
• Agrochemical Synthesis: Used as a building block in the creation of advanced pesticides and herbicides with specific stereochemical requirements.
• Peptidomimetics & Drug Design: Serves as a constrained amino acid analog in the design of peptide-like molecules to enhance metabolic stability and bioavailability.
• Fine Chemical Production: Intermediate for synthesizing specialty chemicals, flavors, and fragrances requiring high-purity chiral precursors.
• Biochemical Research: Tool compound in studying glutamate receptor mechanisms and related neurological pathways.
• Material Science: Potential monomer or cross-linking agent in the development of specialized polymers and dendrimers.

Basic Information

Product Name	Cycloglutamate
CAS No.	24885-60-7
Molecular Formula	C5H7NO4
Molecular Weight	145.11 g/mol
Synonyms	Cycloglutamic Acid; 2-Pyrrolidone-5-carboxylic Acid; 5-Oxo-D-proline; D-Pyroglutamic Acid; (R)-5-Oxopyrrolidine-2-carboxylic Acid; PCA; Pyroglutamate; L-Pyroglutamic Acid (enantiomer); Oxoproline
EINECS	Contact for details

Quality Control

Our Cycloglutamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. Specifications are aligned with research and cGMP-grade requirements for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Specification available upon request
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.