Description

Z-Lys(Boc)-Nh2 CAS NO 24828-95-3 is a protected amino acid derivative, specifically Nα-Carbobenzyloxy-Nε-tert-butoxycarbonyl-L-lysine amide, widely used as a critical building block in peptide synthesis. This compound is essential for researchers and manufacturers requiring high-purity intermediates to ensure the fidelity and yield of complex peptide sequences. It is primarily utilized by the pharmaceutical, biotechnology, and life sciences industries for the development of therapeutic peptides, research reagents, and novel bioactive compounds.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key intermediate for the controlled incorporation of lysine residues with orthogonal side-chain protection.
• Pharmaceutical Research: Building block for the development of peptide-based drugs, hormones, and diagnostic agents.
• Bioconjugation: Used in the preparation of peptide-protein conjugates, antibody-drug conjugates (ADCs), and other bioconjugates.
• Combinatorial Chemistry: Essential reagent in libraries for high-throughput screening and drug discovery.
• Academic & Industrial R&D: Serves as a standard reagent in laboratories for studying peptide structure, function, and synthesis methodologies.

Basic Information

Product Name	Z-Lys(Boc)-Nh2
CAS No.	24828-95-3
Molecular Formula	C₁₉H₂₉N₃O₅
Molecular Weight	379.45 g/mol
Synonyms	Nα-Carbobenzyloxy-Nε-tert-butoxycarbonyl-L-lysine amide; Z-Lys(Boc)-NH₂; Cbz-Lys(Boc)-NH₂; Nα-Z-Nε-Boc-L-lysinamide; Nα-Benzyloxycarbonyl-Nε-tert-butoxycarbonyl-L-lysine amide; (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-((tert-butoxycarbonyl)amino)hexanoic acid (common mis-assignment check); Boc-Lys(Z)-NH₂ (alternate protection order); Fmoc-Lys(Boc)-OH related derivative.
EINECS	Contact for details

Quality Control

Our Z-Lys(Boc)-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation (IR, NMR) to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Optical Rotation [α]²⁰D	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.