Description

Acth (5-14) CAS NO 24828-93-1 is a synthetic peptide fragment corresponding to the 5-14 sequence of the adrenocorticotropic hormone (ACTH). This compound is a critical intermediate and research tool for studying hormone-receptor interactions and developing diagnostic or therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic institutions focused on endocrinology and peptide chemistry.

Application

• Pharmaceutical Research & Development: Serves as a key intermediate in the synthesis of longer ACTH analogs and related peptide hormones for therapeutic exploration.
• Biochemical Assay Development: Used as a standard or reference material in bioassays and immunoassays to measure ACTH activity or antibody specificity.
• Endocrinology Studies: Employed in laboratory research to investigate the structure-activity relationship (SAR) of ACTH and its effects on adrenal cortex stimulation.
• Peptide Chemistry & Conjugation: Acts as a building block for creating labeled peptides (e.g., fluorescent, radioactive) for diagnostic imaging or tracing studies.
• Academic & Clinical Research: Supports fundamental research into stress response mechanisms, corticosteroid regulation, and related metabolic pathways.
• Quality Control Standards: Functions as a certified reference material (CRM) for quality testing in peptide manufacturing processes.

Basic Information

Item	Detail
Product Name	Acth (5-14)
CAS No.	24828-93-1
Molecular Formula	C₄₆H₆₈N₁₂O₁₂S
Molecular Weight	1013.2 g/mol
Synonyms	ACTH (5-14); Adrenocorticotropic Hormone (5-14); Corticotropin (5-14); H-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-OH; ACTH Fragment 5-14; [Gly¹]-ACTH (5-14); Adrenocorticotropin (5-14) Fragment
EINECS	Contact for details

Quality Control

Our Acth (5-14) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry (MS) for identity confirmation, and amino acid analysis (AAA). Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research-grade standards and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Amino Acid Composition	Within ±10% of theoretical
Peptide Content (AAA)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.