Description

Z-Val-Ala-Oh is a protected dipeptide building block, specifically the C-terminal carboxylic acid of the valyl-alanine sequence. This compound is essential for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics, offering precise control over molecular structure. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, proteomics research, and the development of novel therapeutic agents.

Application

• Peptide Synthesis: A key intermediate for the controlled elongation of peptide chains in both research and GMP manufacturing settings.
• Pharmaceutical Research: Used in the discovery and development of peptide-based drugs, including enzyme inhibitors and receptor agonists/antagonists.
• Bioconjugation: Serves as a spacer or linker molecule in the creation of peptide-protein or peptide-small molecule conjugates.
• Biochemical Tool Development: Employed to synthesize substrates for protease and peptidase activity assays.
• Material Science: A precursor for designing peptide-derived biomaterials and self-assembling nanostructures.

Basic Information

Product Name	Z-Val-Ala-Oh
CAS No.	24787-89-1
Molecular Formula	C16H22N2O5
Molecular Weight	322.36 g/mol
Synonyms	Z-Val-Ala-OH; N-Carbobenzoxy-L-valyl-L-alanine; CBZ-L-Valyl-L-alanine; Z-L-Val-L-Ala-OH; Benzyloxycarbonyl-L-valyl-L-alanine; (S)-2-(((Benzyloxy)carbonyl)amino)-3-methyl-N-((S)-1-hydroxy-1-oxopropan-2-yl)butanamide; Nα-CBZ-L-valyl-L-alanine; N-Cbz-L-Val-L-Ala
EINECS	Contact for details

Quality Control

Our Z-Val-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and identity confirmation via IR and NMR spectroscopy. We provide full traceability and a Certificate of Analysis (COA) with every shipment to ensure compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.