Description

Z-Ile-Ala-Oh is a protected dipeptide building block, specifically the Z-protected derivative of the Ile-Ala dipeptide sequence. This compound is a critical intermediate in the synthesis of complex peptides and peptidomimetics, offering precise control over stereochemistry and sequence. It is primarily utilized by research institutions and pharmaceutical companies engaged in peptide drug discovery, biochemical research, and the development of novel therapeutic agents.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key building block for the sequential assembly of longer, more complex peptide chains in both research and GMP manufacturing.
• Solution-Phase Peptide Synthesis: Used in the synthesis of specific peptide fragments or small peptides where solution-phase methodology is preferred.
• Pharmaceutical Intermediate: Serves as a crucial precursor in the research and development of peptide-based active pharmaceutical ingredients (APIs).
• Biochemical Probe Development: Incorporated into custom peptides used to study enzyme-substrate interactions, protein-protein binding, and other biological mechanisms.
• Peptidomimetic Research: Acts as a starting material for creating modified peptide analogs with enhanced stability, bioavailability, or biological activity.
• Academic & Industrial R&D: A standard reagent in laboratories focused on organic synthesis, medicinal chemistry, and structural biology.

Basic Information

Item	Detail
Product Name	Z-Ile-Ala-Oh
CAS No.	24787-83-5
Molecular Formula	C20H28N2O6
Molecular Weight	392.45 g/mol
Synonyms	N-Carbobenzoxy-L-isoleucyl-L-alanine; Z-L-Ile-L-Ala-OH; Cbz-Ile-Ala-OH; Nα-Cbz-L-isoleucyl-L-alanine; Benzyloxycarbonyl-L-isoleucyl-L-alanine; (S)-2-(((Benzyloxy)carbonyl)amino)-N-((S)-1-hydroxy-3-methyl-1-oxopentan-2-yl)propanamide; Z-Ile-Ala; CBZ-ILE-ALA-OH
EINECS	Contact for details

Quality Control

Our Z-Ile-Ala-Oh is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis to confirm stereochemical integrity, ensuring it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.