Description

4-Fluorocinnamaldehyde is a versatile fluorinated aromatic aldehyde building block, essential for introducing the 4-fluorocinnamyl moiety into complex molecular architectures. Its unique structure, combining a reactive α,β-unsaturated carbonyl group with a fluorine substituent, makes it a critical intermediate for synthesizing high-value compounds in advanced research and development. This compound is particularly valuable for pharmaceutical chemists, agrochemical researchers, and material scientists seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry programs targeting CNS disorders, anti-inflammatory agents, and oncology.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated organic semiconductors and liquid crystal compounds for display technologies.
• Flavor & Fragrance Chemistry: Intermediate for creating specialized aromatic aldehydes used in high-value fragrance compositions.
• Organic Synthesis & Cross-Coupling Reactions: A valuable substrate in Heck reactions, Suzuki couplings, and other palladium-catalyzed transformations to create complex, fluorinated styrene derivatives.
• Chemical Research & Development: Used in academic and industrial R&D labs as a standard reagent for studying fluorination effects and developing new synthetic methodologies.

Basic Information

Product Name	4-Fluorocinnamaldehyde
CAS No.	24654-55-5
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	4-Fluorocinnamaldehyde; (E)-3-(4-Fluorophenyl)acrylaldehyde; 3-(4-Fluorophenyl)-2-propenal; p-Fluorocinnamaldehyde; trans-4-Fluorocinnamaldehyde; 4-Fluorobenzylideneacetaldehyde; 2-Propenal, 3-(4-fluorophenyl)-; 4-Fluorocinnal
EINECS	Contact for details

Quality Control

Our 4-Fluorocinnamaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	45 - 50 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.