Description

S-Hexylglutathione is a synthetic, cell-permeable glutathione derivative where the glycine moiety is replaced by a hexyl group. This structural modification enhances its lipophilicity, making it a valuable tool compound for biochemical research and a potential precursor in pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences and fine chemical sectors. The product is supplied under the identifier CAS NO 24425-56-7.

Application

• Biochemical Research: Acts as a potent, cell-permeable inhibitor of glutathione S-transferase (GST) enzymes, crucial for studying detoxification pathways and enzyme kinetics.
• Pharmaceutical Intermediates: Serves as a key building block or precursor in the synthesis of more complex therapeutic agents targeting oxidative stress.
• Enzyme Activity Studies: Used in in vitro and cell-based assays to modulate intracellular glutathione levels and investigate related metabolic processes.
• Reference Standard: Employed as a high-purity analytical standard in HPLC or LC-MS methods for quality control and method validation in related compound analysis.
• Prodrug Development: Investigated for its potential in prodrug strategies designed to enhance the delivery and bioavailability of glutathione-related therapeutics.

Basic Information

Product Name	S-Hexylglutathione
CAS No.	24425-56-7
Molecular Formula	C14H26N3O6S
Molecular Weight	364.44 g/mol
Synonyms	Hexylglutathione; S-Hexyl glutathione; L-γ-Glutamyl-S-hexylcysteinylglycine; γ-Glutamyl-S-hexylcysteinylglycine; GST Inhibitor I; Glutathione S-hexyl ester (common misnomer); NSC 113001; S-n-Hexylglutathione
EINECS	Contact for details

Quality Control

Our S-Hexylglutathione is manufactured under a quality management system and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Standard quality parameters include assay by HPLC, confirmation of structure by spectroscopic methods (NMR, IR), and control of related substances. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment. We can support development projects with material meeting research-grade or higher purity specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content	≤ 5.0% (KF)
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.