Description

S-Ethylglutathione is a synthetic, cell-permeable derivative of the essential antioxidant glutathione, modified with an ethyl group on the sulfur atom. This structural modification enhances its stability and bioavailability, making it a valuable tool in biochemical research and pharmaceutical development. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and nutraceutical industries for studying oxidative stress mechanisms and developing advanced therapeutic formulations.

Application

• Biochemical Research: Used as a stable, cell-permeable precursor in studies of glutathione metabolism, redox signaling, and cellular defense mechanisms against oxidative damage.
• Pharmaceutical Intermediates: Serves as a key building block or active pharmaceutical ingredient (API) in the synthesis of novel drugs targeting conditions related to oxidative stress, such as neurodegenerative diseases.
• Nutraceutical Formulations: Incorporated into advanced dietary supplements designed to support the body's endogenous antioxidant systems and promote cellular health.
• Cosmeceutical Actives: Applied in premium skincare products for its potential anti-aging and protective properties against environmental skin stressors.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC, LC-MS, or NMR analysis of related compounds.
• Enzyme Studies: Acts as a substrate or inhibitor in enzymatic assays for glutathione S-transferases (GSTs) and other related enzymes.

Basic Information

Product Name	S-Ethylglutathione
CAS No.	24425-52-3
Molecular Formula	C12H20N3O6S
Molecular Weight	334.37 g/mol
Synonyms	S-Ethyl-L-glutathione; γ-L-Glutamyl-S-ethyl-L-cysteinylglycine; L-Glutathione, S-ethyl-; Ethylglutathione; S-Et-GSH; NSC 113945; Glutathione S-ethyl ester (common misnomer); S-Ethyl reduced glutathione
EINECS	Contact for details

Quality Control

Our S-Ethylglutathione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and heavy metals. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and results. Our quality commitment ensures material suitable for research and cGMP-grade manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.