Description

Propionyl-Leu-Leu-Arg-Al Hemisulfate is a synthetic peptide derivative, specifically a modified tetrapeptide sequence. This compound is of significant interest in biochemical and pharmaceutical research due to its role as a substrate or inhibitor for various proteolytic enzymes, particularly serine proteases. It is primarily utilized by research institutions, diagnostic kit manufacturers, and pharmaceutical development companies engaged in enzyme kinetics studies, assay development, and drug discovery programs.

Application

• Enzyme Substrate for Research: Used as a specific chromogenic or fluorogenic substrate for studying the activity, kinetics, and inhibition of serine proteases like trypsin, thrombin, and related enzymes.
• Diagnostic Assay Development: Serves as a key component in the formulation of in-vitro diagnostic (IVD) kits for measuring protease activity in clinical and research samples.
• Biochemical Pathway Analysis: Employed in cell biology and biochemistry labs to investigate proteolytic signaling pathways and enzyme function.
• Pharmaceutical Screening: Acts as a tool compound in high-throughput screening (HTS) campaigns to identify novel protease inhibitors for therapeutic applications.
• Quality Control Reagent: Used as a reference standard or calibration material in the quality control of enzyme preparations and related bioproducts.

Basic Information

Product Name	Propionyl-Leu-Leu-Arg-Al Hemisulfate
CAS No.	24365-46-6
Molecular Formula	C24H45N7O6 · ½ H2SO4
Molecular Weight	Contact for details
Synonyms	Propionyl-Leucine-Leucine-Arginine-Alanine Hemisulfate; N-Propionyl-L-leucyl-L-leucyl-L-arginyl-L-alanine Hemisulfate; Propionyl-LLRA-Al Hemisulfate; pLeu-Leu-Arg-Ala Hemisulfate; Substrate for Serine Proteases; Chromogenic Peptide Substrate; Boc-Leu-Leu-Arg-Ala related analog; Protease Research Peptide
EINECS	Contact for details

Quality Control

Our Propionyl-Leu-Leu-Arg-Al Hemisulfate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and specific rotation analysis. A Certificate of Analysis (COA) detailing batch-specific results is provided to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture absorption. For extended storage, consider desiccant in the storage environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.