Description

(2S,3R)-14-Hydroxy-19-Oxo-2,3-[[(2S,3R,6R)-Tetrahydro-3-Hydroxy-6-Methyl-4-Oxo-2H-Pyran-3,2-Diyl]Bisoxy]Card-20(22)-Enolide is a high-purity, structurally complex cardenolide derivative, a class of compounds known for their potent biological activity. This compound is of significant interest for advanced pharmaceutical research and development, particularly in the study of cardiac glycosides and their mechanisms. It serves as a critical reference standard and a valuable pharmaceutical intermediate for synthesizing novel therapeutic agents. Target users include R&D laboratories, pharmaceutical manufacturers, and academic institutions focused on cardiovascular drug discovery and natural product chemistry.

Application

• Pharmaceutical Reference Standard: Used for analytical method development, validation, and quality control in the production of cardiac drugs.
• Active Pharmaceutical Ingredient (API) Intermediate: A key synthetic building block in the manufacture of novel cardenolide-based therapeutics.
• Biochemical Research: Employed in pharmacological studies to investigate sodium-potassium ATPase (Na+/K+-ATPase) inhibition and related cardiac effects.
• Natural Product Synthesis: Serves as a sophisticated starting material or intermediate for the total synthesis of complex natural products.
• Academic & Discovery Research: Utilized in university and institutional labs for exploring new structure-activity relationships (SAR) in medicinal chemistry.

Basic Information

Product Name	(2S,3R)-14-Hydroxy-19-Oxo-2,3-[[(2S,3R,6R)-Tetrahydro-3-Hydroxy-6-Methyl-4-Oxo-2H-Pyran-3,2-Diyl]Bisoxy]Card-20(22)-Enolide
CAS No.	24321-47-9
Molecular Formula	C30H42O10
Molecular Weight	562.65 g/mol
Synonyms	14-Hydroxy-19-oxo-2,3:15,16-bis(3-hydroxy-6-methyl-4-oxotetrahydropyran-2-yl)oxy]card-20(22)-enolide; 3β,14β-Dihydroxy-19-oxo-5β-card-20(22)-enolide 3-(6-deoxy-α-L-talopyranoside); A derivative of Cardenolide; 19-Oxocymarin; 19-Oxocymarol; 3-Epi-19-oxohellebrigenin 3-α-L-rhamnoside; Strophanthidin derivative
EINECS	Contact for details

Quality Control

Our (2S,3R)-14-Hydroxy-19-Oxo-2,3-[[(2S,3R,6R)-Tetrahydro-3-Hydroxy-6-Methyl-4-Oxo-2H-Pyran-3,2-Diyl]Bisoxy]Card-20(22)-Enolide is produced and handled under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic identification (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect this light-sensitive compound from degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.