Description

3,7-Dihydro-1,3-Dimethyl-8-Iodo-1H-Purine-2,6-Dione is a high-purity iodinated xanthine derivative, a key chemical intermediate in advanced organic synthesis. This compound is valued for its unique halogenated purine structure, which is critical for introducing iodine atoms into complex molecular frameworks. It is primarily sought by research institutions and pharmaceutical developers for use in medicinal chemistry, particularly in the synthesis of novel adenosine receptor ligands and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, especially those targeting adenosine receptors (A1, A2A, A2B, A3).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents for neurological, cardiovascular, and inflammatory conditions.
• Biochemical Probe Development: Serves as a precursor for radiolabeled (e.g., with I-125) or fluorescently tagged probes used in biological assays and imaging studies.
• Organic Synthesis: Employed as a specialized reagent for introducing iodine into heterocyclic systems, enabling further cross-coupling reactions (e.g., Suzuki, Sonogashira).
• Academic & Industrial R&D: Utilized in basic research to explore the chemical and biological properties of modified purines and xanthines.

Basic Information

Product Name	3,7-Dihydro-1,3-Dimethyl-8-Iodo-1H-Purine-2,6-Dione
CAS No.	24255-56-9
Molecular Formula	C7H7IN4O2
Molecular Weight	306.06 g/mol
Synonyms	8-Iodotheophylline; 1,3-Dimethyl-8-iodoxanthine; 8-Iodo-1,3-dimethylxanthine; 8-Iodo-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione; 8-Iodotheophyllin; 8-Iodo-1,3,7-trimethylxanthine (common misnomer); 8-Iodo-1,3-dimethyl-3,7-dihydro-1H-purine-2,6-dione; 8-Iodo-DMPX
EINECS	Contact for details

Quality Control

Our 3,7-Dihydro-1,3-Dimethyl-8-Iodo-1H-Purine-2,6-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment ensures the material is suitable for demanding research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.