Description

L-4-Iodophenylalanine is a halogenated derivative of the essential amino acid phenylalanine, featuring an iodine atom at the para position of the aromatic ring. This structural modification makes it a valuable non-natural amino acid and a critical chiral building block in organic synthesis and pharmaceutical research. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors. Its unique properties facilitate the development of novel compounds for therapeutic and diagnostic applications.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of peptide-based drugs, enzyme inhibitors, and radiopharmaceuticals.
• Bioconjugation & Labeling: Used in the preparation of labeled peptides and proteins for biochemical research, imaging, and diagnostic assays.
• Organocatalyst & Ligand Precursor: Serves as a precursor for chiral catalysts and ligands used in asymmetric synthesis.
• Metabolic Studies: Employed as a tracer or analog in metabolic pathway research and biochemical studies.
• Agrochemical Research: A building block for developing novel active ingredients with specific biological activity.
• Material Science: Incorporated into specialty polymers and advanced materials to impart specific functional properties.

Basic Information

Product Name	L-4-Iodophenylalanine
CAS No.	24250-85-9
Molecular Formula	C9H10INO2
Molecular Weight	291.09 g/mol
Synonyms	L-4-Iodo-DL-phenylalanine; (S)-2-Amino-3-(4-iodophenyl)propanoic acid; p-Iodo-L-phenylalanine; 4-Iodo-L-phenylalanine; L-4-Iodophenylalanine; L-p-Iodophenylalanine; (S)-4-Iodophenylalanine; Fmoc-L-4-iodophenylalanine (precursor form)
EINECS	Contact for details

Quality Control

Our L-4-Iodophenylalanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets high-purity standards suitable for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and specific impurity profiles is provided with every shipment to guarantee traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.